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Frequencies of clinically important CYP2C19 and CYP2D6 alleles are graded across Europe

CYP2C19 and CYP2D6 are important drug-metabolizing enzymes that are involved in the metabolism of around 30% of all medications. Importantly, the corresponding genes are highly polymorphic and these genetic differences contribute to interindividual and interethnic differences in drug pharmacokinetic...

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Publicat a:Eur J Hum Genet
Autors principals: Petrović, Jelena, Pešić, Vesna, Lauschke, Volker M.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906321/
https://ncbi.nlm.nih.gov/pubmed/31358955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-019-0480-8
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