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Chemokine CCR5 and cocaine interactions in the brain: cocaine enhances mesolimbic CCR5 mRNA levels and produces place preference and locomotor activation that are reduced by a CCR5 antagonist

C-C chemokine receptor type 5, also known as CCR5 or CD195, is best known as a viral co-receptor that facilitates entry of HIV into cells. Evidence that CCR5 knockout mice display fewer dopamine neurons, lower striatal dopamine levels, and reduced locomotor activation compared to wild types also sug...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Nayak, Sunil U, Cicalese, Stephanie, Tallarida, Chris, Oliver, Chicora F., Rawls, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906231/
https://ncbi.nlm.nih.gov/pubmed/31557508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2019.09.017
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