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Chemokines and cocaine: CXCR4 receptor antagonist AMD3100 attenuates cocaine place preference and locomotor stimulation in rats

Plasma levels of the chemokine CXCL12 are elevated in mice following acute cocaine exposure and decreased in human cocaine abusers during withdrawal. CXCL12 is also one of the few chemokines located in the brain and can modulate dopamine transmission through activation of its receptor CXCR4. To asse...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Kim, Jae, Connelly, Krista L., Unterwald, Ellen M., Rawls, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326690/
https://ncbi.nlm.nih.gov/pubmed/27575003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.08.015
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