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Failures in Protein Clearance Partly Underlie Late Onset Neurodegenerative Diseases and Link Pathology to Genetic Risk

As we identify the loci involved in late onset neurodegenerative disease, we are finding that the majority of them are involved in damage response processes. In this short review, I propose that it is partly a failure in these damage response processes which underlie late onset disease and that the...

詳細記述

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書誌詳細
出版年:Front Neurosci
第一著者: Hardy, John
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906158/
https://ncbi.nlm.nih.gov/pubmed/31866813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01304
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