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Failures in Protein Clearance Partly Underlie Late Onset Neurodegenerative Diseases and Link Pathology to Genetic Risk

As we identify the loci involved in late onset neurodegenerative disease, we are finding that the majority of them are involved in damage response processes. In this short review, I propose that it is partly a failure in these damage response processes which underlie late onset disease and that the...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Autor principal: Hardy, John
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906158/
https://ncbi.nlm.nih.gov/pubmed/31866813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01304
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