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Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

Experimental models of the human brain are needed for basic understanding of its development and disease(1). Human brain organoids hold unprecedented promise for this purpose; however, they are plagued by high organoid-to-organoid variability(2,3). This has raised doubts as to whether developmental...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Velasco, Silvia, Kedaigle, Amanda J., Simmons, Sean K., Nash, Allison, Rocha, Marina, Quadrato, Giorgia, Paulsen, Bruna, Nguyen, Lan, Adiconis, Xian, Regev, Aviv, Levin, Joshua Z., Arlotta, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906116/
https://ncbi.nlm.nih.gov/pubmed/31168097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1289-x
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