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Differential orientation and conformation of surface-bound keratinocyte growth factor on (hydroxyethyl)methacrylate, (hydroxyethyl)methacrylate/methyl methacrylate, and (hydroxyethyl)methacrylate/methacrylic acid hydrogel copolymers

The development of hydrogels for protein delivery requires protein–hydrogel interactions that cause minimal disruption of the protein’s biological activity. Biological activity can be influenced by factors such as orientational accessibility for receptor binding and conformational changes, and these...

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Publicat a:Biointerphases
Autors principals: Sen-Britain, Shohini, Hicks, Wesley L., Hard, Robert, Gardella, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: American Vacuum Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905655/
https://ncbi.nlm.nih.gov/pubmed/30360629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1116/1.5051655
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