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Differential orientation and conformation of surface-bound keratinocyte growth factor on (hydroxyethyl)methacrylate, (hydroxyethyl)methacrylate/methyl methacrylate, and (hydroxyethyl)methacrylate/methacrylic acid hydrogel copolymers
The development of hydrogels for protein delivery requires protein–hydrogel interactions that cause minimal disruption of the protein’s biological activity. Biological activity can be influenced by factors such as orientational accessibility for receptor binding and conformational changes, and these...
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| Veröffentlicht in: | Biointerphases |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Vacuum Society
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6905655/ https://ncbi.nlm.nih.gov/pubmed/30360629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1116/1.5051655 |
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