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Site-selective acylation of natural products with BINOL-derived phosphoric acids

The site-selective acylation of a steroidal natural product 19-hydroxydehydroepiandrosterone catalyzed by 1,1’-Bi(2-napthol)-derived (BINOL) chiral phosphoric acids (CPA’s) is described. Systematic variation and multivariate linear regression analysis reveal that the same steric parameters typically...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Li, Junqi, Grosslight, Samantha, Miller, Scott J., Sigman, Matthew S., Toste, F. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905390/
https://ncbi.nlm.nih.gov/pubmed/31827975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.9b03535
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