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Neuregulin-1 Protects Neuronal Cells Against Damage due to CoCl(2)-Induced Hypoxia by Suppressing Hypoxia-Inducible Factor-1α and P53 in SH-SY5Y Cells

PURPOSE: Hypoxia-mediated neurotoxicity contributes to various neurodegenerative disorders, including Alzheimer disease. Neuregulin-1 (NRG1) plays an important role in the development and plasticity of the brain. The aim of the present study was to investigate the neuroprotective effect and the regu...

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Detalhes bibliográficos
Publicado no:Int Neurourol J
Main Authors: Yoo, Seung-Yeon, Yoo, Ji-Young, Kim, Han-Byeol, Baik, Tai-Kyoung, Lee, Jun-Ho, Woo, Ran-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Continence Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905208/
https://ncbi.nlm.nih.gov/pubmed/31795610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5213/inj.1938190.095
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