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Necrostatin-1 protects C2C12 myotubes from CoCl(2)-induced hypoxia

Necrostatin-1 (Nec-1) is a selective and potent allosteric inhibitor of necroptosis by specifically inhibiting the activity of receptor-interacting protein (RIP) 1 kinase. The aim of the present study was to determine the effect of Nec-1 on an anoxia model comprising mouse skeletal C2C12 myotubes. I...

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Dades bibliogràfiques
Publicat a:Int J Mol Med
Autors principals: Chen, Rui, Xu, Jiehua, She, Yanling, Jiang, Ting, Zhou, Shanyao, Shi, Huacai, Li, Cheng
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846651/
https://ncbi.nlm.nih.gov/pubmed/29436688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3466
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