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Effects of Cobalt Chloride, a Hypoxia-Mimetic Agent, on Autophagy and Atrophy in Skeletal C2C12 Myotubes

BACKGROUND: Hypoxia-induced autophagy and muscle wasting occur in several environmental and pathological conditions. However, the molecular mechanisms underlying the effects of the hypoxia-mimetic agent CoCl(2) on autophagy and muscle atrophy are still unclear. METHODS: C2C12 myotubes were exposed t...

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Publicat a:Biomed Res Int
Autors principals: Chen, Rui, Jiang, Ting, She, Yanling, Xu, Jiehua, Li, Cheng, Zhou, Shanyao, Shen, Huijuan, Shi, Huacai, Liu, Shuang
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494548/
https://ncbi.nlm.nih.gov/pubmed/28706950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7097580
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