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H3K36 Methylation and the Chromodomain Protein Eaf3 Are Required for Proper Cotranscriptional Spliceosome Assembly

In the eukaryotic cell, spliceosomes assemble onto pre-mRNA cotranscriptionally. Spliceosome assembly takes place in the context of the chromatin environment, suggesting that the state of the chromatin may affect splicing. The molecular details and mechanisms through which chromatin affects splicing...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Leung, Calvin S., Douglass, Stephen M., Morselli, Marco, Obusan, Matthew B., Pavlyukov, Marat S., Pellegrini, Matteo, Johnson, Tracy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904931/
https://ncbi.nlm.nih.gov/pubmed/31242410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.100
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