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Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements
Assembly of the spliceosome onto pre-mRNA is a dynamic process involving the ordered exchange of snRNPs to form the catalytically active spliceosome. These ordered rearrangements have recently been shown to occur cotranscriptionally, while the RNA polymerase is still actively engaged with the chroma...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033250/ https://ncbi.nlm.nih.gov/pubmed/21245291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011982108 |
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