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An Optimized Surfactant-Based PEG-PLCL In Situ Gel Formulation For Enhanced Activity Of Rosuvastatin In Poloxamer-Induced Hyperlipidemic Rats
BACKGROUND: Injectable in situ gel (ISG) systems suffer from high initial drug release that may result in toxic effects. OBJECTIVE: This work aimed to develop an injectable sustained release rosuvastatin (RSV) ISG formulation with minimum initial drug burst and improved hyperlipidemic efficacy. METH...
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| 出版年: | Drug Des Devel Ther |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6904902/ https://ncbi.nlm.nih.gov/pubmed/31839704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S224442 |
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