A Cohesin-Mediated Intrachromosomal Loop Drives Oncogenic ROR lncRNA to Accelerate Tumorigenesis

Long noncoding RNAs (lncRNAs) are an important class of pervasive noncoding RNA involved in a variety of biological functions. Numerous studies have demonstrated their important regulatory role in human disease, especially cancer. However, the mechanism underlying the transcription of lncRNAs is not...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Fan, Jiayan, Xu, Yangfan, Wen, Xuyang, Ge, Shengfang, Jia, Renbing, Zhang, He, Fan, Xianqun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904803/
https://ncbi.nlm.nih.gov/pubmed/31451355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.07.020
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