A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells

The generation of insulin-producing cells (IPCs) from pluripotent stem cells could be a breakthrough treatment for type 1 diabetes. However, development of new techniques is needed to exclude immature cells for clinical application. Dithizone staining is used to evaluate IPCs by detecting zinc. We h...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ohta, Shogo, Ikemoto, Tetsuya, Wada, Yuma, Saito, Yu, Yamada, Shinichiro, Imura, Satoru, Morine, Yuji, Shimada, Mitsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904733/
https://ncbi.nlm.nih.gov/pubmed/31822724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55172-0
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