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HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis

BACKGROUND: The role of hypoxia-inducible factor-1α (HIF-1α) in primary colorectal cancer (CRC) and colorectal liver metastasis (CRLM) has remained unclear. The aim of this study was to investigate HIF-1α expression and its association with prognosis in patients with CRLM with a focus on hepatic ste...

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Detalhes bibliográficos
Publicado no:World J Surg Oncol
Main Authors: Wada, Yuma, Morine, Yuji, Imura, Satoru, Ikemoto, Tetsuya, Saito, Yu, Takasu, Chie, Yamada, Shinichiro, Shimada, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487629/
https://ncbi.nlm.nih.gov/pubmed/32895059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-020-02012-5
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