Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling

Lifestyle factors are important drivers of chronic diseases, including cardiovascular syndromes, with low grade inflammation as a central player. Attenuating myeloperoxidase (MPO) activity, an inflammatory enzyme associated with obesity, hypertension and heart failure, could have protective effects...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Piek, Arnold, Koonen, Debby P. Y., Schouten, Elisabeth-Maria, Lindtstedt, Eva L., Michaëlsson, Erik, de Boer, Rudolf A., Silljé, Herman H. W.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904581/
https://ncbi.nlm.nih.gov/pubmed/31822739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55263-y
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