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Transcriptional correlates of the pathological phenotype in a Huntington’s disease mouse model
Huntington disease (HD) is a fatal neurodegenerative disorder without a cure that is caused by an aberrant expansion of CAG repeats in exon 1 of the huntingtin (HTT) gene. Although a negative correlation between the number of CAG repeats and the age of disease onset is established, additional factor...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6904489/ https://ncbi.nlm.nih.gov/pubmed/31822756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55177-9 |
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