Transcriptional correlates of the pathological phenotype in a Huntington’s disease mouse model

Huntington disease (HD) is a fatal neurodegenerative disorder without a cure that is caused by an aberrant expansion of CAG repeats in exon 1 of the huntingtin (HTT) gene. Although a negative correlation between the number of CAG repeats and the age of disease onset is established, additional factor...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Gallardo-Orihuela, Andrea, Hervás-Corpión, Irati, Hierro-Bujalance, Carmen, Sanchez-Sotano, Daniel, Jiménez-Gómez, Gema, Mora-López, Francisco, Campos-Caro, Antonio, Garcia-Alloza, Monica, Valor, Luis M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904489/
https://ncbi.nlm.nih.gov/pubmed/31822756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55177-9
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