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The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development

Human-specific gene duplications (HSGDs) have recently emerged as key modifiers of brain development and evolution. However, the molecular mechanisms underlying the function of HSGDs remain often poorly understood. In humans, a truncated duplication of SRGAP2A led to the emergence of two human-speci...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Schmidt, Ewoud R. E., Kupferman, Justine V., Stackmann, Michelle, Polleux, Franck
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904453/
https://ncbi.nlm.nih.gov/pubmed/31822692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54887-4
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