Mapping Alterations Induced by Long-Term Axenic Cultivation of Leishmania amazonensis Promastigotes With a Multiplatform Metabolomic Fingerprint Approach

Leishmaniases are widespread neglected diseases with an incidence of 1.6 million new cases and 40 thousand deaths per year. Leishmania parasites may show distinct, species-specific patterns of virulence that lead to different clinical manifestations. It is well known that successive in vitro passage...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Crepaldi, Frederico, de Toledo, Juliano Simões, do Carmo, Anderson Oliveira, Ferreira Marques Machado, Leopoldo, de Brito, Daniela Diniz Viana, Serufo, Angela Vieira, Almeida, Ana Paula Martins, de Oliveira, Leandro Gonzaga, Ricotta, Tiago Queiroga Nery, Moreira, Douglas de Souza, Murta, Silvane Maria Fonseca, Diniz, Ariane Barros, Menezes, Gustavo Batista, López-Gonzálvez, Ángeles, Barbas, Coral, Fernandes, Ana Paula
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904349/
https://ncbi.nlm.nih.gov/pubmed/31867285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00403
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