Mapping Alterations Induced by Long-Term Axenic Cultivation of Leishmania amazonensis Promastigotes With a Multiplatform Metabolomic Fingerprint Approach

Leishmaniases are widespread neglected diseases with an incidence of 1.6 million new cases and 40 thousand deaths per year. Leishmania parasites may show distinct, species-specific patterns of virulence that lead to different clinical manifestations. It is well known that successive in vitro passage...

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Publicado en:Front Cell Infect Microbiol
Autores principales: Crepaldi, Frederico, de Toledo, Juliano Simões, do Carmo, Anderson Oliveira, Ferreira Marques Machado, Leopoldo, de Brito, Daniela Diniz Viana, Serufo, Angela Vieira, Almeida, Ana Paula Martins, de Oliveira, Leandro Gonzaga, Ricotta, Tiago Queiroga Nery, Moreira, Douglas de Souza, Murta, Silvane Maria Fonseca, Diniz, Ariane Barros, Menezes, Gustavo Batista, López-Gonzálvez, Ángeles, Barbas, Coral, Fernandes, Ana Paula
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904349/
https://ncbi.nlm.nih.gov/pubmed/31867285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00403
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