Sequestration of Late Antigens Within Viral Factories Impairs MVA Vector-Induced Protective Memory CTL Responses

Cytotoxic CD8+ T cell (CTL) responses play an essential role in antiviral immunity. Here, we focused on the activation of CTL which recognize epitopes derived from viral or recombinant antigens with either early or late expression kinetics after infection with Modified Vaccinia Virus Ankara (MVA). L...

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Vydáno v:Front Immunol
Hlavní autoři: Tao, Sha, Tao, Ronny, Busch, Dirk H., Widera, Marek, Schaal, Heiner, Drexler, Ingo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904312/
https://ncbi.nlm.nih.gov/pubmed/31867011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02850
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