Efficient Induction of Cytotoxic T Cells by Viral Vector Vaccination Requires STING-Dependent DC Functions

Modified Vaccinia virus Ankara (MVA) is an attenuated strain of vaccinia virus and currently under investigation as a promising vaccine vector against infectious diseases and cancer. MVA acquired mutations in host range and immunomodulatory genes, rendering the virus deficient for replication in mos...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Barnowski, Cornelia, Ciupka, Gregor, Tao, Ronny, Jin, Lei, Busch, Dirk H., Tao, Sha, Drexler, Ingo
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381110/
https://ncbi.nlm.nih.gov/pubmed/32765505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01458
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