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Design of a basigin-mimicking inhibitor targeting the malaria invasion protein RH5

Many human pathogens use host cell-surface receptors to attach and invade cells. Often, the host-pathogen interaction affinity is low, presenting opportunities to block invasion using a soluble, high-affinity mimic of the host protein. The Plasmodium falciparum reticulocyte-binding protein homolog 5...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Warszawski, Shira, Dekel, Elya, Campeotto, Ivan, Marshall, Jennifer M., Wright, Katherine E., Lyth, Oliver, Knop, Orli, Regev-Rudzki, Neta, Higgins, Matthew K, Draper, Simon J, Baum, Jake, Fleishman, Sarel J
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904230/
https://ncbi.nlm.nih.gov/pubmed/31325330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25786
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