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Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk
BACKGROUND: Muscle wasting from chronic kidney disease (CKD) or from defective insulin signalling results in morbidity and, ultimately, mortality. We have identified an endogenous mediator of insulin resistance, signal regulatory protein alpha (SIRPα), which leads to cachexia in mice and is associat...
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| Publicado no: | J Cachexia Sarcopenia Muscle |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6903446/ https://ncbi.nlm.nih.gov/pubmed/31507080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12459 |
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