ULK2 is essential for degradation of ubiquitinated protein aggregates and homeostasis in skeletal muscle

Basal protein turnover, which largely relies on the degradation of ubiquitinated substrates, is instrumental for maintenance of muscle mass and function. However, the regulation of ubiquitinated protein degradation in healthy, nonatrophying skeletal muscle is still evolving, and potential tissue-spe...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Fuqua, Jordan D., Mere, Caleb P., Kronemberger, Ana, Blomme, Jay, Bae, Dam, Turner, Kristen D., Harris, Matthew P., Scudese, Estevão, Edwards, Mitchell, Ebert, Scott M., de Sousa, Luís G. O., Bodine, Sue C., Yang, Ling, Adams, Christopher M., Lira, Vitor A.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902739/
https://ncbi.nlm.nih.gov/pubmed/31361156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900766R
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