IL-6/p-BTK/p-ERK signaling mediates calcium phosphate–induced pruritus

Uremic pruritus with elevated levels of calcium phosphate (CaP) in skin is a common symptom in patients with chronic kidney disease (CKD). In this study, we demonstrate that intradermal injection of CaP into mice triggered scratching by up-regulating the IL-6 in skin and phosphorylation of ERKs in d...

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Gardado en:
Detalles Bibliográficos
Publicado en:FASEB J
Main Authors: Keshari, Sunita, Sipayung, Apriska Dewi, Hsieh, Ching-Chuan, Su, Li-Jen, Chiang, Yun-Ru, Chang, Huan-Cheng, Yang, Wu-Chang, Chuang, Tsung-Hsien, Chen, Chien-Lung, Huang, Chun-Ming
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902723/
https://ncbi.nlm.nih.gov/pubmed/31365830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900016RR
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