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Attenuation of amyloid-β generation by atypical protein kinase C–mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35
Amyloid-β (Aβ) is derived from the proteolytic processing of amyloid precursor protein (APP), and the deposition of extracellular Aβ to form amyloid plaques is a pathologic hallmark of Alzheimer’s disease (AD). Although reducing Aβ generation and accumulation has been proposed as a means of treating...
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| Publicat a: | FASEB J |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Federation of American Societies for Experimental Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6902715/ https://ncbi.nlm.nih.gov/pubmed/31373844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802825RR |
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