Attenuation of amyloid-β generation by atypical protein kinase C–mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35

Amyloid-β (Aβ) is derived from the proteolytic processing of amyloid precursor protein (APP), and the deposition of extracellular Aβ to form amyloid plaques is a pathologic hallmark of Alzheimer’s disease (AD). Although reducing Aβ generation and accumulation has been proposed as a means of treating...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Chau, Dennis Dik-Long, Yung, Kristen Wing-Yu, Chan, William Wai-Lun, An, Ying, Hao, Yan, Chan, Ho-Yin Edwin, Ngo, Jacky Chi-Ki, Lau, Kwok-Fai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902715/
https://ncbi.nlm.nih.gov/pubmed/31373844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802825RR
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