BMP9 directly induces rapid GSK3-β phosphorylation in a Wnt-independent manner through class I PI3K-Akt axis in osteoblasts

Bone morphogenetic protein (BMP)9 has been reported to be the most potent BMP to induce bone formation. However, the details of BMP9-transduced intracellular signaling remain ambiguous. Here, we have investigated signal transduction mechanisms of BMP9 in comparison to BMP2, another potent inducer of...

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Bibliografische gegevens
Gepubliceerd in:FASEB J
Hoofdauteurs: Eiraku, Nahoko, Chiba, Norika, Nakamura, Toshiaki, Amir, Muhammad Subhan, Seong, Chang-Hwan, Ohnishi, Tomokazu, Kusuyama, Joji, Noguchi, Kazuyuki, Matsuguchi, Tetsuya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2019
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902712/
https://ncbi.nlm.nih.gov/pubmed/31365832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900733RR
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