Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low–molecular weight protein tyrosine phosphatase

Osteopontin (OPN) is an osteogenic marker protein. Osteoblast functions are affected by inflammatory cytokines and pathological conditions. OPN is highly expressed in bone lesions such as those in rheumatoid arthritis. However, local regulatory effects of OPN on osteoblasts remain ambiguous. Here we...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Kusuyama, Joji, Bandow, Kenjiro, Ohnishi, Tomokazu, Hisadome, Mitsuhiro, Shima, Kaori, Semba, Ichiro, Matsuguchi, Tetsuya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2017
Onderwerpen:
Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426847/
https://ncbi.nlm.nih.gov/pubmed/28331074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0716
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items