Noninvasive longitudinal quantification of β-cell mass with [(111)In]-labeled exendin-4

Currently, quantifying β-cell mass (BCM) requires harvesting the pancreas. In this study, we investigated a potential noninvasive method to quantify BCM changes longitudinally using [Lys(12)((111)In-BnDTPA-Ahx)]exendin-4 ([(111)In]-Ex4) and single-photon emission computed tomography (SPECT). We used...

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Vydáno v:FASEB J
Hlavní autoři: Fujita, Naotaka, Fujimoto, Hiroyuki, Hamamatsu, Keita, Murakami, Takaaki, Kimura, Hiroyuki, Toyoda, Kentaro, Saji, Hideo, Inagaki, Nobuya
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902711/
https://ncbi.nlm.nih.gov/pubmed/31370679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900555RR
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