Investigation of the preservation effect of canagliflozin on pancreatic beta cell mass using SPECT/CT imaging with (111)In-labeled exendin-4

Radiolabeled exendin derivatives are promising for non-invasive quantification of pancreatic beta cell mass (BCM); longitudinal observation of BCM for evaluation of therapeutic effects has not been achieved. The aim of this study is to demonstrate the usefulness of our developing method using [Lys(1...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hamamatsu, Keita, Fujimoto, Hiroyuki, Fujita, Naotaka, Murakami, Takaaki, Shiotani, Masaharu, Toyoda, Kentaro, Inagaki, Nobuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893013/
https://ncbi.nlm.nih.gov/pubmed/31797889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54722-w
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