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Combining MAP-1:CD35 or MAP-1:CD55 fusion proteins with pattern-recognition molecules as novel targeted modulators of the complement cascade

Dysregulation of the complement system is involved in the pathogenesis of several diseases, and its inhibition has been shown to be a feasible therapeutic option. Therefore, there is an interest in the development of complement modulators to treat complement activation–related inflammatory pathologi...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Pérez-Alós, Laura, Bayarri-Olmos, Rafael, Skjoedt, Mikkel-Ole, Garred, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902692/
https://ncbi.nlm.nih.gov/pubmed/31469600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901643R
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