T-cell–derived extracellular vesicles regulate B-cell IgG production via pyruvate kinase muscle isozyme 2

Intercellular communication between lymphocytes plays a fundamental role in numerous immune responses. Previously, we demonstrated that hyperhomocysteinemia (HHcy) induced T cell intracellular glycolytic-lipogenic reprogramming and IFN-γ secretion via pyruvate kinase muscle isozyme 2 (PKM2) to accel...

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Vydáno v:FASEB J
Hlavní autoři: Yang, Juan, Dang, Guohui, Lü, Silin, Liu, Huiying, Ma, Xiaolong, Han, Lulu, Deng, Jiacheng, Miao, Yutong, Li, Xiaopeng, Shao, Fangyu, Jiang, Changtao, Xu, Qingbo, Wang, Xian, Feng, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902684/
https://ncbi.nlm.nih.gov/pubmed/31480861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900863R
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