GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation

The adaptive immune system plays a critical role in hyperhomocysteinemia (HHcy)-accelerated atherosclerosis. Recent studies suggest that HHcy aggravates atherosclerosis with elevated oxidative stress and reduced S-nitrosylation level of redox-sensitive protein residues in the vasculature. However, w...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Li, Jing, Zhang, Yan, Zhang, Yuying, Lü, Silin, Miao, Yutong, Yang, Juan, Huang, Shenming, Ma, Xiaolong, Han, Lulu, Deng, Jiacheng, Fan, Fangfang, Liu, Bo, Huo, Yong, Xu, Qingbo, Chen, Chang, Wang, Xian, Feng, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007174/
https://ncbi.nlm.nih.gov/pubmed/29860106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.04.021
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