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Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF
Protein tyrosine kinase 7 (PTK7), a catalytically defective receptor protein tyrosine kinase (RPTK), plays an oncogenic role by activating an unidentified TKI-258 (dovitinib)-sensitive RPTK in esophageal squamous cell carcinoma (ESCC) cells. Here, we demonstrate that among TKI-258–sensitive RPTKs, f...
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| Udgivet i: | FASEB J |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6902674/ https://ncbi.nlm.nih.gov/pubmed/31490704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900932R |
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