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A liquid chromatography with tandem mass spectrometry method for simultaneous determination of UTL-5g and its metabolites in human plasma
UTL-5g is a novel small-molecule TNF-α inhibitor under investigation as both a chemoprotective and radioprotective agent. Animal studies showed that pretreatment of UTL-5g protected kidney, liver, and platelets from cisplatin-induced toxicity. In addition, UTL-5g reduced liver and lung injuries indu...
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| Udgivet i: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6902638/ https://ncbi.nlm.nih.gov/pubmed/25955381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.04.015 |
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