Insights into pneumococcal fratricide from the crystal structures of the modular killing factor LytC

The first structure of a pneumococcal autolysin, that of the LytC lysozyme, has been solved in ternary complex with choline and a pneumococcal peptidoglycan (PG) fragment. The active site of the hydrolase module is not fully exposed but is oriented toward the choline-binding module, which accounts f...

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Publicado en:Nat Struct Mol Biol
Autores principales: Pérez-Dorado, Inmaculada, González, Ana, Morales, María, Sanles, Reyes, Striker, Waldemar, Vollmer, Waldemar, Mobashery, Shahriar, García, José L, Martínez-Ripoll, Martín, García, Pedro, Hermoso, Juan A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902435/
https://ncbi.nlm.nih.gov/pubmed/20400948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1817
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