Spatiotemporally Skewed Activation of Programmed Cell Death Receptor 1–Positive T Cells after Epstein-Barr Virus Infection and Tumor Development in Long-Term Fully Humanized Mice

Humanized mice developing functional human T cells endogenously and capable of recognizing cognate human leukocyte antigen–matched tumors are emerging as relevant models for studying human immuno-oncology in vivo. Herein, mice transplanted with human CD34(+) stem cells and bearing endogenously devel...

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Udgivet i:Am J Pathol
Main Authors: Danisch, Simon, Slabik, Constanze, Cornelius, Angela, Albanese, Manuel, Tagawa, Takanobu, Chen, Yen-Fu A., Krönke, Nicole, Eiz-Vesper, Britta, Lienenklaus, Stefan, Bleich, Andre, Theobald, Sebastian J., Schneider, Andreas, Ganser, Arnold, von Kaisenberg, Constantin, Zeidler, Reinhard, Hammerschmidt, Wolfgang, Feuerhake, Friedrich, Stripecke, Renata
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902117/
https://ncbi.nlm.nih.gov/pubmed/30593822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.11.014
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