CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease

Epstein-Barr virus (EBV) is a latent and oncogenic human herpesvirus. Lytic viral protein expression plays an important role in EBV-associated malignancies. The EBV envelope glycoprotein 350 (gp350) is expressed abundantly during EBV lytic reactivation and sporadically on the surface of latently inf...

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Publicado no:Mol Ther Oncolytics
Main Authors: Slabik, Constanze, Kalbarczyk, Maja, Danisch, Simon, Zeidler, Reinhard, Klawonn, Frank, Volk, Valery, Krönke, Nicole, Feuerhake, Friedrich, Ferreira de Figueiredo, Constanca, Blasczyk, Rainer, Olbrich, Henning, Theobald, Sebastian J., Schneider, Andreas, Ganser, Arnold, von Kaisenberg, Constantin, Lienenklaus, Stefan, Bleich, Andre, Hammerschmidt, Wolfgang, Stripecke, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479496/
https://ncbi.nlm.nih.gov/pubmed/32953984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.08.005
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