Yes-Associated Protein 1 Plays Major Roles in Pancreatic Stellate Cell Activation and Fibroinflammatory Responses

Background: Yes-associated protein 1 (YAP), a transcriptional co-activator and major effector of the Hippo pathway, regulates cell differentiation and morphology in many cell types and supports aberrant tumor growth. Recent studies showed that YAP is expressed in pancreas tissues in pancreatic ducta...

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Pubblicato in:Front Physiol
Autori principali: Hu, Cheng, Yang, Jiayue, Su, Hsin-Yuan, Waldron, Richard T., Zhi, Mengmeng, Li, Ling, Xia, Qing, Pandol, Stephen J., Lugea, Aurelia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901825/
https://ncbi.nlm.nih.gov/pubmed/31849712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01467
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