Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic co-culture

Transcription factor (TF)-based reprogramming of somatic tissues holds great promise for regenerative medicine. Previously we demonstrated that the TFs GATA2, GFI1B, and FOS convert mouse and human fibroblasts to hemogenic endothelial-like precursors that generate Hematopoietic Stem Progenitor (HSPC...

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Détails bibliographiques
Publié dans:FEBS Lett
Auteurs principaux: Daniel, Michael G., Sachs, David, Bernitz, Jeffrey M., Fstkchyan, Yesai, Rapp, Katrina, Satija, Namita, Law, Kenneth, Patel, Foram, Gomes, Andreia M., Kim, Huen-Suk, Pereira, Carlos-Filipe, Chen, Benjamin, Lemischka, Ihor R., Moore, Kateri A.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901732/
https://ncbi.nlm.nih.gov/pubmed/31557312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13621
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