Caveolin-1 Controls Vesicular TLR2 Expression, p38 Signaling and T Cell Suppression in BCG Infected Murine Monocytic Myeloid-Derived Suppressor Cells

Monocytic myeloid-derived suppressor cells (M-MDSCs) and granulocytic MDSCs (G-MDSCs) have been found to be massively induced in TB patients as well in murine Mtb infection models. However, the interaction of mycobacteria with MDSCs and its role in TB infection is not well studied. Here, we investig...

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Опубликовано в: :Front Immunol
Главные авторы: John, Vini, Kotze, Leigh A., Ribechini, Eliana, Walzl, Gerhard, Du Plessis, Nelita, Lutz, Manfred B.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901706/
https://ncbi.nlm.nih.gov/pubmed/31849990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02826
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