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Constrained De Novo Sequencing of neo-Epitope Peptides using Tandem Mass Spectrometry
Neoepitope peptides are newly formed antigens presented by major histocompatibility complex class I (MHC-I) on cell surfaces. The cells presenting neoepitope peptides are recognized and subsequently killed by cytotoxic T-cells. Immunopeptidomic approaches aim to characterize the peptide repertoire (...
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| Publié dans: | Res Comput Mol Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901291/ https://ncbi.nlm.nih.gov/pubmed/31819927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-89929-9_9 |
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