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Constrained De Novo Sequencing of neo-Epitope Peptides using Tandem Mass Spectrometry

Neoepitope peptides are newly formed antigens presented by major histocompatibility complex class I (MHC-I) on cell surfaces. The cells presenting neoepitope peptides are recognized and subsequently killed by cytotoxic T-cells. Immunopeptidomic approaches aim to characterize the peptide repertoire (...

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Detalhes bibliográficos
Publicado no:Res Comput Mol Biol
Main Authors: Li, Sujun, DeCourcy, Alex, Tang, Haixu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901291/
https://ncbi.nlm.nih.gov/pubmed/31819927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-89929-9_9
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