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GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors
G protein-coupled receptors (GPCRs) are the most widely targeted gene family for Food and Drug Administration (FDA)-approved drugs. To assess possible roles for GPCRs in cancer, we analyzed The Cancer Genome Atlas (TCGA) data for mRNA expression, mutations, and copy number variation (CNV) in 20 cate...
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| Gepubliceerd in: | PLoS Biol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901242/ https://ncbi.nlm.nih.gov/pubmed/31765370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000434 |
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