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CoCo: RNA-seq read assignment correction for nested genes and multimapped reads

MOTIVATION: Next-generation sequencing techniques revolutionized the study of RNA expression by permitting whole transcriptome analysis. However, sequencing reads generated from nested and multi-copy genes are often either misassigned or discarded, which greatly reduces both quantification accuracy...

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Vydáno v:Bioinformatics
Hlavní autoři: Deschamps-Francoeur, Gabrielle, Boivin, Vincent, Abou Elela, Sherif, Scott, Michelle S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901076/
https://ncbi.nlm.nih.gov/pubmed/31141144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz433
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